产品货号：
Z12406
中文名称：
CAND1抗体
英文名称：
Anti-CAND1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CAND1 Antibody |
| 指标别名 | CAND1,Cullin associated NEDD8 dissociated protein 1,p120 CAND1,TATA binding protein interacting protein,20A,TBP interacting protein,TBP interacting protein of 120kDa A,TIP120 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IP,WB |
| 基因名称 | CAND1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 11-24 of Human CAND1/TIP120A (N-terminal) coupled to KLH. |
| 成分 | 0.01% (w/v) Sodium Azide |
| 纯化方式 | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.This product reacts with human,rat and mouse CAND1/TIP120A.Cross-reactivity does occur with human,rat and mouse CAND2/TIP120B.Cross-reactivity with CAND1 from other sources is not known. |
| 浓度 | 85mg/mL by Refractometry |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | CAND1 is also known as TIP120A,and TATA-binding protein-interacting protein 120A.The SCF complex consists of the invariable components Skp1,Cul1,and Rbx1 as well as a variable F-box protein,and functions as an E3 ubiquitin ligase.E3 ubiquitin ligases regulate various physiological processes.CAND1 binds to Cul1 and potentially regulates the SCF complex.CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1.CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation.CAND1 forms a ternary complex with CUL1 and ROC1. |
| Uniprot ID | Q86VP6 |
| 推荐稀释比 | ELISA:1:2,000 - 1:10,000 IHC:User Optimized IP:User Optimized WB:1:500 - 1:1,000 |
相关搜索：CAND1抗体，CAND1多抗，Anti-CAND1 Antibody